Patient Considerations & Involvement
Patient preferences
DCTs may be less burdensome for participants than conventional trials, as travel to the research site is reduced or eliminated and trial visits can be carried out from the participant’s home or immediate vicinity by applying digital technologies and operational innovations. To tailor DCT elements to patients and lower the participation burden, we need to understand what the preferences are for participation in clinical trials with different levels of decentralisation.
Recommendations
How Trials@Home reached these recommendations
To investigate what motivates people to participate in a clinical trial from home, we first conducted focus group discussions. We identified main drivers for trial participation, which provided a basis for the quantification of the importance of these drivers through a patient preference study. Preference data were obtained in a discrete choice experiment (DCE), which enabled us to gain insights into participation preferences and to estimate acceptance rates for different hypothetical trial scenarios. We were also able to identify differences in preferences among individuals and to determine which characteristics impact these preferences.
Further reading
Publications
What motivates people living with type 2 diabetes mellitus to participate in clinical trials from home? Findings from a multi-country focus group study on decentralised clinical trial approaches.
Kopanz, et al |
Clinical and Translational Science |
2024 |
|---|