Peer reviews & research outputs
All papers published as a result of the work done in the Trials@Home will be published here.
The impact of operational trial approaches on representativeness: Comparison of decentralized clinical trial participants, conventional trial participants, and patients in daily practice
First published: February 2025
Authors: Amos J. de Jong, Mira G.P. Zuidgeest, Yared Santa-Ana-Tellez, Christine E. Hallgreen, Thomas T. van Sloten, Anthonius de Boer, Helga Gardarsdottir, the Trials@Home Consortium
Why do Diabetic Participants Enroll in Clinical Trials?
First published: 28 January 2025
Authors: Julia Kopanz, Bart Lagerwaard, PhD, and Mira Zuidgeest, PhD
Regulatory readiness to facilitate the appropriate use of innovation in clinical trials: The case of decentralized clinical trial approaches
First published: November 2024
Authors: Amos J. de Jong, Mira G.P. Zuidgeest, Yared Santa-Ana-Tellez, Anthonius de Boer, Helga Gardarsdottir, the Trials@Home Consortium
The Digital Platform and Its Emerging Role in Decentralized Clinical Trials
First published: 3 September 2024
Authors: Rachel R Copland; Sten Hanke; Amy Rogers; Lampros Mpaltadoros; Ioulietta Lazarou; Alexandra Zeltsi; Spiros Nikolopoulos; Thomas M MacDonald; Isla S Mackenzie
The Ethics of Decentralized Clinical Trials and Informed Consent: Taking Technologies’ Soft Impacts into Account
First published: 30 April 2024
Authors: Tessa I. van Rijssel · Ghislaine J. M. W. van Thiel ·
Johannes J. M. van Delden · On behalf of the Trials@Home consortium
Technology Support System and Review Process for a Decentralized Clinical Trial: Trials@Home, RADIAL DCT as Case Study
First published: 21 February 2024
Authors: Sten Hanke, Dimitrios Giannikopoulos, Hannes Hilberger, Theresa Weitlaner and Bernhard Neumayer
Which Benefits Can Justify Risks in Research?
First published: 5 January 2024
Authors: Tessa I. van Rijssel, Ghislaine J. M. W. van Thiel, Helga Gardarsdottir, Johannes J. M. van Delden, on behalf of the Trials@Home consortium
Opportunities and challenges for decentralized clinical trial approaches: European health technology assessment perspective
First published: 1 December 2023
Authors: Amos J. de Jong, MSc, Nadi Shahid, BSc, Mira G.P. Zuidgeest, PhD, Yared Santa-Ana-Tellez, PhD, Milou Hogervorst, PharmD, Wim Goettsch, PhD, Hamidou Traore, PhD, Anthonius de Boer, PhD, Helga Gardarsdottir, PhD, on behalf of theTrials@Home Consortium
Direct-to-Participant Investigational Medicinal Product Supply in Clinical Trials in Europe – Exploring the Experiences of Sponsors, Site Staff, and Couriers
First published: 12 July 2023
Decentralised, patient-centric, site-less, virtual, and digital clinical trials? From confusion to consensus
First published: 6 February 2023
Green light for clinical research at patients’ homes?
Studies at patients’ homes may improve accessibility and inclusiveness of drug research
(white paper)
First published: 24 January 2023
A cross‑sectional survey on the early impact of COVID‑19 on the uptake of decentralised trial methods in the conduct of clinical trials
First published: 11 October 2022
Which decentralised trial activities are reported in clinical trial protocols of drug trials initiated in 2019–2020? A cross-sectional study in ClinicalTrials.gov
First published: 29 August 2022
A secondary qualitative analysis of stakeholder views about participant recruitment, retention, and adherence in decentralised clinical trials (DCTs)
First published: 30 July 2022
Ethics review of decentralized clinical trials (DCTs): Results of a mock ethics review
First published: 20 July 2022
Opportunities and Challenges for Decentralized Clinical Trials: European Regulators’ Perspective
First published: 30 April 2022
A Systematic Review of Methods used to Conduct Decentralised Clinical Trials
First published: 27 December 2021
An Overview of Technology Availability to Support Remote Decentralized Clinical Trials
First published: 28 September 2021
Learning from remote decentralised clinical trial experiences: A qualitative analysis of interviews with trial personnel, patient representatives and other stakeholders
First published: 13 July 2021
Authors: Joanne Coyle, Amy Rogers, Rachel Copland, Giorgia De Paoli, Thomas M. MacDonald, Isla S. Mackenzie, on behalf of the Trials@HomeConsortium